Why Dupuytren’s Disease is More Common in Northerners – The Answer Lies in Neanderthal Genes

Despite the genetic predisposition, disease development also depends on other factors such as age, diabetes, and alcohol abuse. The presence of Neanderthal genes increases the risk by approximately 2.8 times, but does not guarantee disease development. This study sheds light on the ancient evolutionary history of the disease, opening new possibilities for diagnosis and therapy aimed at specific biological mechanisms.

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