Interactions between LncRNAs and MAPK Signaling Pathways in Breast Cancer Pathogenesis

Long non-coding RNAs (lncRNAs) play crucial roles in cancer biology by modulating gene expression and cellular processes. In breast cancer, characterized by various genetic and epigenetic changes, the mitogen-activated protein kinase (MAPK) signaling pathway is vital for controlling cell proliferation, survival, and metastasis. Recent studies have shed light on the intricate connections between lncRNAs and MAPK signaling molecules such as ERK, p38, and JNK, unveiling new regulatory mechanisms in breast cancer pathogenesis. These interactions often involve lncRNAs either regulating MAPK pathway activity or participating in cross-talk with other oncogenic pathways.